Irreversible alteration

{
  "id": "MLC-T-CHM-006160",
  "term": "Irreversible alteration",
  "field": "Chemistry",
  "definition": "A change in a biological system or organism that cannot be reversed or repaired, leading to permanent damage or dysfunction. This type of alteration persists even after the removal of the causative agent. Such changes are often observed in chronic toxicity or severe acute exposures.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1247 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/irreversible-alteration/"
}