Chronic toxicity

{
  "id": "MLC-T-CHM-002065",
  "term": "Chronic toxicity",
  "field": "Chemistry",
  "definition": "Adverse effects that occur as a result of repeated or continuous exposure to a substance over a long period, representing a substantial portion of an organism's lifespan. These effects develop slowly and persist or progress even after exposure ceases, contrasting with acute toxicity from short-term exposure. Regulatory testing for chronic toxicity in rodents for carcinogenicity assessment is conducted over a two-year period.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "adverse effect",
    "exposure"
  ],
  "references": [
    "PAC, 2004, 76, 1033. 'Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003)' on page 1044 (https://doi.org/10.1351/pac200476051033)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/chronic-toxicity/"
}