Chronic

{
  "id": "MLC-T-CHM-002058",
  "term": "Chronic",
  "field": "Chemistry",
  "definition": "Describing conditions, processes, or exposures that are persistent or long-lasting in their effects. In toxicology, it pertains to adverse effects that occur after repeated or continuous exposure to a substance over a prolonged period. A chronic exposure duration for rodents in laboratory studies is defined as lasting for the major portion of the animal's lifespan, typically 18 to 24 months.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1583. 'Explanatory dictionary of key terms in toxicology (IUPAC Recommendations 2007)' on page 1595 (https://doi.org/10.1351/pac200779091583)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/chronic/"
}