First-in-class

{
  "id": "MLC-T-CHM-013106",
  "term": "First-in-class",
  "field": "Chemistry",
  "definition": "Describing a drug that uses a new and unique mechanism of action to treat a medical condition. Such a therapeutic agent is the first one to be approved by a regulatory authority, like the FDA, that targets a specific biological pathway or molecule previously unexploited for that indication. Subsequent drugs with the same mechanism of action are not considered first-in-class.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1735 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/first-in-class/"
}