MLchartDataset catalogue

Drug repurposing

Term · Chemistry · MLC-T-CHM-003449

The process of identifying new therapeutic uses for existing drugs that have already been approved for other indications. This strategy involves investigating known compounds for activity against different diseases, potentially accelerating drug development by bypassing early-stage safety and toxicity testing. A notable example is sildenafil, originally developed for angina, now used for erectile dysfunction.

Table 1. Record
IdentifierMLC-T-CHM-003449
FieldChemistry
SubjectChemistry and Human Health
Synonymsdrug repositioning; drug reprofiling
ReferencesPAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1733 (https://doi.org/10.1351/PAC-REC-12-11-23)
Record as JSON
{
  "id": "MLC-T-CHM-003449",
  "term": "Drug repurposing",
  "field": "Chemistry",
  "definition": "The process of identifying new therapeutic uses for existing drugs that have already been approved for other indications. This strategy involves investigating known compounds for activity against different diseases, potentially accelerating drug development by bypassing early-stage safety and toxicity testing. A notable example is sildenafil, originally developed for angina, now used for erectile dysfunction.",
  "synonyms": [
    "drug repositioning",
    "drug reprofiling"
  ],
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1733 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/drug-repurposing/"
}

Record 3,665 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.