MLchartDataset catalogue

Drug metabolizing enzyme

Term · Chemistry · MLC-T-CHM-003448

An enzyme that modifies xenobiotics, including drugs, through biochemical reactions, altering their activity, solubility, and excretion profile. These enzymes are primarily found in the liver and are responsible for the metabolism of most pharmaceuticals. The cytochrome P450 (CYP) superfamily, such as the CYP3A4 enzyme, is a major class of drug metabolizing enzymes in humans.

Table 1. Record
IdentifierMLC-T-CHM-003448
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 745 (https://doi.org/10.1515/pac-2015-1202)
Record as JSON
{
  "id": "MLC-T-CHM-003448",
  "term": "Drug metabolizing enzyme",
  "field": "Chemistry",
  "definition": "An enzyme that modifies xenobiotics, including drugs, through biochemical reactions, altering their activity, solubility, and excretion profile. These enzymes are primarily found in the liver and are responsible for the metabolism of most pharmaceuticals. The cytochrome P450 (CYP) superfamily, such as the CYP3A4 enzyme, is a major class of drug metabolizing enzymes in humans.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 745 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/drug-metabolizing-enzyme/"
}

Record 3,664 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.