Follow-on drug

Term · Chemistry · MLC-T-CHM-004574

A drug that acts through the same or a similar mechanism as an existing, previously approved drug, often developed by a different company and sometimes called a me-too drug. Its chemical structure can differ from the original, and it aims to offer better efficacy, fewer side effects or a different route or schedule of administration. It is distinct from a generic drug, which is a copy of an off-patent medicine with the same active ingredient.

Table 1. Record
Identifier	MLC-T-CHM-004574
Field	Chemistry
Subject	Chemistry and Human Health
References	PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1735 (https://doi.org/10.1351/PAC-REC-12-11-23)
See also	Analogue; Analogue-based drug discovery; First-in-class

Record as JSON

{
  "id": "MLC-T-CHM-004574",
  "term": "Follow-on drug",
  "field": "Chemistry",
  "definition": "A drug that acts through the same or a similar mechanism as an existing, previously approved drug, often developed by a different company and sometimes called a me-too drug. Its chemical structure can differ from the original, and it aims to offer better efficacy, fewer side effects or a different route or schedule of administration. It is distinct from a generic drug, which is a copy of an off-patent medicine with the same active ingredient.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "analogue",
    "analogue-based drug discovery",
    "first-in-class"
  ],
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1735 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/follow-on-drug/"
}

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