Fractional-factorial design

{
  "id": "MLC-T-CHM-004632",
  "term": "Fractional-factorial design",
  "field": "Chemistry",
  "definition": "An experimental design that uses a selected subset of the runs from a full factorial design. This approach is used when the number of factors to be investigated is large, making a full design impractical due to the high number of required experiments. A key characteristic of this design is the confounding or aliasing of effects, where main effects become indistinguishable from certain higher-order interactions.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "experimental design",
    "Plackett-Burman design",
    "alias structure",
    "full-factorial design"
  ],
  "references": [
    "PAC, 2016, 88, 407. 'Vocabulary of concepts and terms in chemometrics (IUPAC Recommendations 2016)' on page 415 (https://doi.org/10.1515/pac-2015-0605)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/fractional-factorial-design/"
}