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Halogen bond

Term · Chemistry · MLC-T-CHM-005082

A non-covalent interaction between an electrophilic region on a halogen atom (X) and a nucleophilic region on another atom (Y). The electrophilic region, known as the sigma-hole, is located along the extension of the covalent bond to the halogen. This interaction is increasingly recognized for its role in crystal engineering and drug design.

Table 1. Record
IdentifierMLC-T-CHM-005082
FieldChemistry
SubjectOrganic and Biomolecular Chemistry
ReferencesPAC, 2022, 94, 353. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)' on page 427 (https://doi.org/10.1515/pac-2018-1010)
Record as JSON
{
  "id": "MLC-T-CHM-005082",
  "term": "Halogen bond",
  "field": "Chemistry",
  "definition": "A non-covalent interaction between an electrophilic region on a halogen atom (X) and a nucleophilic region on another atom (Y). The electrophilic region, known as the sigma-hole, is located along the extension of the covalent bond to the halogen. This interaction is increasingly recognized for its role in crystal engineering and drug design.",
  "subject": "Organic and Biomolecular Chemistry",
  "references": [
    "PAC, 2022, 94, 353. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)' on page 427 (https://doi.org/10.1515/pac-2018-1010)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/halogen-bond/"
}

Record 5,385 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.