Hit rate

{
  "id": "MLC-T-CHM-005322",
  "term": "Hit rate",
  "field": "Chemistry",
  "definition": "The fraction of the compounds run through a screening assay that show the sought activity at or beyond a cutoff chosen in advance, quoted as a percentage of all compounds screened. Its value depends on the assay, the target and the make-up of the library. In drug discovery campaigns it commonly lies between about 0.1 percent and a few percent.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "hit threshold"
  ],
  "references": [
    "PAC, 2011, 83, 1129. 'Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)' on page 1143 (https://doi.org/10.1351/PAC-REC-09-05-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/hit-rate/"
}