Idiosyncrasy

{
  "id": "MLC-T-CHM-005580",
  "term": "Idiosyncrasy",
  "field": "Chemistry",
  "definition": "A genetically determined, qualitatively abnormal reaction to a chemical, which is not dose-related in the typical sense and occurs in a small fraction of individuals. This type of adverse response is distinct from both allergy, which involves a specific immune mechanism, and toxicity, which affects most individuals at a sufficient dose. An example is the prolonged muscle paralysis experienced by individuals with a specific genetic trait after receiving the muscle relaxant succinylcholine.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1241 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/idiosyncrasy/"
}