Idiosyncratic drug reaction

{
  "id": "MLC-T-CHM-005581",
  "term": "Idiosyncratic drug reaction",
  "field": "Chemistry",
  "definition": "An adverse drug reaction that is qualitatively or quantitatively different from the expected pharmacological effects of the drug and occurs in a susceptible individual. These reactions are not dose-dependent and are not predictable from the known pharmacology of the drug. They are often attributed to genetic predispositions affecting drug metabolism or immune responses.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "adverse drug reaction"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1181 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/idiosyncratic-drug-reaction/"
}