Linear free energy relationship

{
  "id": "MLC-T-CHM-006622",
  "term": "Linear free energy relationship",
  "field": "Chemistry",
  "definition": "A correlation that relates the logarithm of a rate or equilibrium constant for one series of reactions to the logarithm of a corresponding constant for another series of reactions, or to a substituent constant. These relationships are based on the assumption that changes in free energy for a reaction are linearly related to changes in the free energy of activation or equilibrium for a related process. The Hammett equation is a well-known example, correlating reaction rates with electronic properties of substituents.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2009, 81, 829. 'Glossary of terms used in ecotoxicology (IUPAC Recommendations 2009)' on page 906 (https://doi.org/10.1351/PAC-REC-08-07-09)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/linear-free-energy-relationship/"
}