Linear epitope

{
  "id": "MLC-T-CHM-006621",
  "term": "Linear epitope",
  "field": "Chemistry",
  "definition": "An antigenic determinant on a protein that is recognized by an antibody or T cell receptor, where the amino acid residues forming the epitope are contiguous in the primary sequence of the protein. Unlike conformational epitopes, which depend on the protein's three-dimensional structure, linear epitopes remain accessible even after denaturation. These epitopes are often targeted by antibodies generated during viral infections or in response to peptide vaccines.",
  "synonyms": [
    "continuous epitope"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T lymphocyte"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1202 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/linear-epitope/"
}