Monospecificity
Term · Chemistry · MLC-T-CHM-013306
The property of an antiserum or antibody preparation of reacting only with its designated antigen, with no detectable reaction to other antigens under the assay conditions. A monospecific antiserum can be polyclonal and recognise several epitopes on that one antigen, whereas a monoclonal antibody is directed at a single epitope.
| Identifier | MLC-T-CHM-013306 |
|---|---|
| Field | Chemistry |
| Subject | Analytical Chemistry |
| References | PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1142 (https://doi.org/10.1515/pac-2016-1120) |
| See also | Immunoreactivity; Immunochemical specificity |
Record as JSON
{
"id": "MLC-T-CHM-013306",
"term": "Monospecificity",
"field": "Chemistry",
"definition": "The property of an antiserum or antibody preparation of reacting only with its designated antigen, with no detectable reaction to other antigens under the assay conditions. A monospecific antiserum can be polyclonal and recognise several epitopes on that one antigen, whereas a monoclonal antibody is directed at a single epitope.",
"subject": "Analytical Chemistry",
"see_also": [
"immunoreactivity",
"immunochemical specificity"
],
"references": [
"PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1142 (https://doi.org/10.1515/pac-2016-1120)"
],
"url": "https://mlchart.com/terminology/chemistry/monospecificity/"
}
Record 8,023 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.