Loading dose

Term · Chemistry · MLC-T-CHM-006727

An initial higher dose of a drug given at the beginning of treatment to rapidly achieve a therapeutic concentration in the body. This approach is used for drugs with a long half-life or when immediate therapeutic effects are required. It is followed by smaller maintenance doses to sustain the desired drug level.

Table 1. Record
Identifier	MLC-T-CHM-006727
Field	Chemistry
Subject	Chemistry and Human Health
References	PAC, 2009, 81, 971. 'Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009)' on page 989 (https://doi.org/10.1351/PAC-REC-04-10-14)

Record as JSON

{
  "id": "MLC-T-CHM-006727",
  "term": "Loading dose",
  "field": "Chemistry",
  "definition": "An initial higher dose of a drug given at the beginning of treatment to rapidly achieve a therapeutic concentration in the body. This approach is used for drugs with a long half-life or when immediate therapeutic effects are required. It is followed by smaller maintenance doses to sustain the desired drug level.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2009, 81, 971. 'Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009)' on page 989 (https://doi.org/10.1351/PAC-REC-04-10-14)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/loading-dose/"
}

Record 7,126 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.