Therapeutic index

{
  "id": "MLC-T-CHM-011927",
  "term": "Therapeutic index",
  "field": "Chemistry",
  "definition": "A quantitative measure that compares the dose of a drug that causes a therapeutic effect to the dose that causes toxicity. It is typically expressed as the ratio of the toxic dose (TD50) to the effective dose (ED50), or the lethal dose (LD50) to the effective dose (ED50). A higher therapeutic index indicates a wider margin of safety for the drug.",
  "synonyms": [
    "therapeutic ratio"
  ],
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1753 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/therapeutic-index/"
}