Loading of a property

{
  "id": "MLC-T-CHM-006728",
  "term": "Loading of a property",
  "field": "Chemistry",
  "definition": "The weight showing how strongly an original variable, such as a molecular descriptor, contributes to a given component in principal component analysis or to a latent variable in partial least squares. Descriptors with large absolute loadings dominate that component, so loadings reveal which properties drive differences among compounds in a QSAR data set. The loadings are the coefficients of the linear combination that forms the component.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2016, 88, 239. 'Glossary of terms used in computational drug design, part II (IUPAC Recommendations 2015)' on page 249 (https://doi.org/10.1515/pac-2012-1204)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/loading-of-a-property/"
}