Maximum tolerable dose

{
  "id": "MLC-T-CHM-007058",
  "term": "Maximum tolerable dose",
  "field": "Chemistry",
  "definition": "The largest dose of a chemical that causes no deaths among treated test animals, written LD0. It lies below the LD50, the dose lethal to half of the animals, and survivors at this dose may still show sublethal toxicity. It differs from the maximum tolerated dose, which is chosen for chronic studies to produce limited but non-lethal toxicity.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 1993, 65, 2003. 'Glossary for chemists of terms used in toxicology (IUPAC Recommendations 1993)' on page 2067 (https://doi.org/10.1351/pac199365092003)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/maximum-tolerable-dose/"
}