Minimum significant difference

{
  "id": "MLC-T-CHM-007400",
  "term": "Minimum significant difference",
  "field": "Chemistry",
  "definition": "The smallest difference between the mean of a control group and the mean of a treatment group that is statistically significant at a specified alpha level. It is used in hypothesis testing to determine the lowest concentration of a substance that produces a detectable effect compared to the untreated control. This value is calculated following an analysis of variance (ANOVA) and depends on the chosen significance level (e.g., p < 0.05), the sample size, and the variability within the data.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2009, 81, 829. 'Glossary of terms used in ecotoxicology (IUPAC Recommendations 2009)' on page 916 (https://doi.org/10.1351/PAC-REC-08-07-09)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/minimum-significant-difference/"
}