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Pleiotropism

Term · Chemistry · MLC-T-CHM-009037

The phenomenon where a single gene affects multiple, seemingly unrelated phenotypic traits. This occurs when a gene product is involved in several different biochemical pathways or developmental processes. An example is Marfan syndrome, where a mutation in a single gene affects the skeletal, cardiovascular, and ocular systems.

Table 1. Record
IdentifierMLC-T-CHM-009037
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 793 (https://doi.org/10.1515/pac-2015-1202)
Record as JSON
{
  "id": "MLC-T-CHM-009037",
  "term": "Pleiotropism",
  "field": "Chemistry",
  "definition": "The phenomenon where a single gene affects multiple, seemingly unrelated phenotypic traits. This occurs when a gene product is involved in several different biochemical pathways or developmental processes. An example is Marfan syndrome, where a mutation in a single gene affects the skeletal, cardiovascular, and ocular systems.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 793 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/pleiotropism/"
}

Record 9,600 of 13,678 in Chemistry terminology (MLC-0109). Request the full dataset.