Germ cell gene mutation assay

{
  "id": "MLC-T-CHM-004857",
  "term": "Germ cell gene mutation assay",
  "field": "Chemistry",
  "definition": "A laboratory test designed to detect heritable genetic changes in the reproductive cells of an organism. This assay assesses the ability of a chemical or agent to induce mutations in sperm or egg cells, which can then be passed on to offspring. Such assays are performed in vivo, often using rodent models.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "germ line cell",
    "somatic",
    "transgenic"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 760 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/germ-cell-gene-mutation-assay/"
}