Reverse mutation

{
  "id": "MLC-T-CHM-010315",
  "term": "Reverse mutation",
  "field": "Chemistry",
  "definition": "A genetic mutation that restores the original wild-type sequence or function that was lost due to a previous forward mutation. This can occur through a second mutation at the same site or at a different site that suppresses the effect of the first mutation. It is a key principle in the Ames test for mutagenicity.",
  "synonyms": [
    "back mutation"
  ],
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1302 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/reverse-mutation/"
}