Gene knockout

{
  "id": "MLC-T-CHM-004808",
  "term": "Gene knockout",
  "field": "Chemistry",
  "definition": "A genetic technique in which a specific gene in an organism is inactivated or deleted. This process typically involves homologous recombination to replace or disrupt the target gene sequence. It is used to study the function of genes by observing the phenotypic effects of their absence.",
  "synonyms": [
    "gene targeting"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "knockout",
    "knockout mouse"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1169 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/gene-knockout/"
}