Knockout mouse

{
  "id": "MLC-T-CHM-006374",
  "term": "Knockout mouse",
  "field": "Chemistry",
  "definition": "A genetically engineered mouse in which a specific gene has been inactivated or deleted from its genome. This allows researchers to study the function of the targeted gene by observing the phenotypic changes in the mouse. These models are widely used in biomedical research to understand human diseases and gene function.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1199 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/knockout-mouse/"
}