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Nude mouse

Term · Chemistry · MLC-T-CHM-008151

A specific strain of laboratory mouse characterized by a genetic mutation that results in an absent or severely underdeveloped thymus gland. This deficiency leads to a compromised immune system, particularly lacking mature T lymphocytes. Nude mice are extensively used in immunology and cancer research as models for studying tumor growth, transplantation, and the effects of immunomodulatory drugs.

Table 1. Record
IdentifierMLC-T-CHM-008151
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1223 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoT lymphocyte
Record as JSON
{
  "id": "MLC-T-CHM-008151",
  "term": "Nude mouse",
  "field": "Chemistry",
  "definition": "A specific strain of laboratory mouse characterized by a genetic mutation that results in an absent or severely underdeveloped thymus gland. This deficiency leads to a compromised immune system, particularly lacking mature T lymphocytes. Nude mice are extensively used in immunology and cancer research as models for studying tumor growth, transplantation, and the effects of immunomodulatory drugs.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T lymphocyte"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1223 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/nude-mouse/"
}

Record 8,658 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.