Inbred strain

{
  "id": "MLC-T-CHM-005752",
  "term": "Inbred strain",
  "field": "Chemistry",
  "definition": "An animal population resulting from at least 20 consecutive generations of brother-sister matings or a comparable level of controlled breeding. This intensive inbreeding leads to a high degree of homozygosity, making individuals within the strain genetically almost identical to one another. The C57BL/6 mouse is a widely used inbred strain in toxicology and biomedical research to minimize genetic variability as a confounding factor.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 768 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/inbred-strain/"
}