Congenic

{
  "id": "MLC-T-CHM-002428",
  "term": "Congenic",
  "field": "Chemistry",
  "definition": "Describing organisms, particularly strains of laboratory animals like mice, that are genetically identical except for a short segment of a single chromosome. These strains are created through a systematic process of repeated backcrossing to an inbred parental strain while selecting for a specific genetic locus from a donor strain. Congenic strains are used to isolate and study the function of a particular gene or genetic region, such as a major histocompatibility complex, in a controlled genetic background.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1148 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/congenic/"
}