Reverse genetics

{
  "id": "MLC-T-CHM-010311",
  "term": "Reverse genetics",
  "field": "Chemistry",
  "definition": "An experimental approach that begins with a known gene sequence and then investigates its function by altering the gene and observing the resulting phenotypic changes. This method contrasts with forward genetics, which starts with a phenotype and seeks to identify the underlying gene. Techniques like gene knockout or RNA interference are commonly used in reverse genetics.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "forward genetics"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 801 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/reverse-genetics/"
}