Knockout

{
  "id": "MLC-T-CHM-006373",
  "term": "Knockout",
  "field": "Chemistry",
  "definition": "An organism in which a specific gene has been inactivated or deleted from its genome through genetic engineering techniques. This results in the complete absence of the functional gene product, allowing researchers to study the gene's role. The genetic alteration is permanent and can be passed on to offspring.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "knockout mouse"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1199 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/knockout/"
}