Somatic gene conversion

{
  "id": "MLC-T-CHM-011044",
  "term": "Somatic gene conversion",
  "field": "Chemistry",
  "definition": "A non-reciprocal transfer of genetic information from one DNA sequence to another homologous sequence within a somatic cell, resulting in the alteration of the recipient sequence. This process can contribute to genetic diversity, particularly in the immune system, where it is a mechanism for generating antibody diversity in some species. It involves the repair of a double-strand break using a homologous template.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1246 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/somatic-gene-conversion/"
}