Variable gene

{
  "id": "MLC-T-CHM-012515",
  "term": "Variable gene",
  "field": "Chemistry",
  "definition": "A segment of DNA that encodes the variable region of an immunoglobulin or T-cell receptor protein. These genes undergo somatic recombination with diversity and joining gene segments to generate the vast diversity of antigen-binding sites. There are multiple variable gene segments in the genome, contributing to immune repertoire diversity.",
  "synonyms": [
    "V Gene"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T-cell receptor",
    "diversity gene",
    "joining gene",
    "variable region"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1258 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/variable-gene/"
}