Joining gene

{
  "id": "MLC-T-CHM-006287",
  "term": "Joining gene",
  "field": "Chemistry",
  "definition": "A segment of DNA that encodes a part of the variable region of an immunoglobulin or T-cell receptor. These gene segments are recombined with variable and diversity gene segments during V(D)J recombination to generate antibody and T-cell receptor diversity. There are multiple joining gene segments available for selection in the genome.",
  "synonyms": [
    "J gene"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T-cell receptor",
    "V(D)J recombination",
    "antigen receptor",
    "constant region",
    "diversity gene",
    "heavy chain",
    "hypervariable region",
    "light chain",
    "variable gene",
    "variable region"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1197 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/joining-gene/"
}