MLchartDataset catalogue

Diversity gene

Term · Chemistry · MLC-T-CHM-003356

A specific gene segment, also known as a D gene, that contributes to the variability of immunoglobulin and T-cell receptor genes. These segments are found between the variable (V) and joining (J) gene segments. During V(D)J recombination, one D gene segment is randomly selected and joined to V and J segments, forming a unique antigen-binding site.

Table 1. Record
IdentifierMLC-T-CHM-003356
FieldChemistry
SubjectChemistry and Human Health
SynonymsD gene
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1158 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoT-cell receptor; V(D)J recombination; Heavy chain; Joining gene; Variable gene
Record as JSON
{
  "id": "MLC-T-CHM-003356",
  "term": "Diversity gene",
  "field": "Chemistry",
  "definition": "A specific gene segment, also known as a D gene, that contributes to the variability of immunoglobulin and T-cell receptor genes. These segments are found between the variable (V) and joining (J) gene segments. During V(D)J recombination, one D gene segment is randomly selected and joined to V and J segments, forming a unique antigen-binding site.",
  "synonyms": [
    "D gene"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T-cell receptor",
    "V(D)J recombination",
    "heavy chain",
    "joining gene",
    "variable gene"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1158 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/diversity-gene/"
}

Record 3,568 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.