MLchartDataset catalogue

Diversity

Term · Chemistry · MLC-T-CHM-013046

The structural dissimilarity among molecules within a collection, such as a chemical library used for drug discovery. Diversity is assessed by comparing molecular properties like size, shape, flexibility, and the distribution of functional groups and pharmacophores. A high degree of structural diversity increases the probability of finding compounds with novel biological activities or modes of action, contrasting with focused libraries that contain structurally similar compounds.

Table 1. Record
IdentifierMLC-T-CHM-013046
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1732 (https://doi.org/10.1351/PAC-REC-12-11-23)
Record as JSON
{
  "id": "MLC-T-CHM-013046",
  "term": "Diversity",
  "field": "Chemistry",
  "definition": "The structural dissimilarity among molecules within a collection, such as a chemical library used for drug discovery. Diversity is assessed by comparing molecular properties like size, shape, flexibility, and the distribution of functional groups and pharmacophores. A high degree of structural diversity increases the probability of finding compounds with novel biological activities or modes of action, contrasting with focused libraries that contain structurally similar compounds.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1732 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/diversity/"
}

Record 3,567 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.