Hypervariable region

{
  "id": "MLC-T-CHM-005534",
  "term": "Hypervariable region",
  "field": "Chemistry",
  "definition": "A segment within the variable region of an antibody or T-cell receptor that exhibits a high degree of amino acid sequence diversity among different individuals. These regions are responsible for antigen binding specificity, allowing the immune system to recognize a vast array of foreign molecules. There are typically three hypervariable regions, also known as complementarity-determining regions (CDRs), in each variable domain.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T-cell receptor",
    "major histocompatibility complex molecule",
    "variable region"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1180 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/hypervariable-region/"
}