Complementarity-determining region

{
  "id": "MLC-T-CHM-002316",
  "term": "Complementarity-determining region",
  "field": "Chemistry",
  "definition": "A hypervariable segment within the variable regions of antibody and T-cell receptor proteins that directly binds to antigens. These regions are responsible for the specificity and diversity of antigen recognition by the immune system. Each antibody or T-cell receptor typically contains three such regions in both its heavy and light chains.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "hypervariable region",
    "T-cell receptor",
    "major histocompatibility complex",
    "variable region"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1147 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/complementarity-determining-region/"
}