Quantum mechanics/molecular mechanics

{
  "id": "MLC-T-CHM-009763",
  "term": "Quantum mechanics/molecular mechanics",
  "field": "Chemistry",
  "definition": "A computational approach that combines quantum mechanics (QM) for a chemically reactive region of a system with molecular mechanics (MM) for the larger, less reactive surrounding environment. This hybrid method allows for accurate description of bond breaking and formation while efficiently treating the bulk of the system. QM/MM methods are widely used in enzyme catalysis and condensed phase simulations.",
  "synonyms": [
    "QC/MM"
  ],
  "subject": "Organic and Biomolecular Chemistry",
  "see_also": [
    "chromophore"
  ],
  "references": [
    "PAC, 2007, 79, 293. 'Glossary of terms used in photochemistry, 3rd edition (IUPAC Recommendations 2006)' on page 406 (https://doi.org/10.1351/pac200779030293)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/quantum-mechanics-molecular-mechanics/"
}