Bioavailability

{
  "id": "MLC-T-ENV-003131",
  "term": "Bioavailability",
  "field": "Environment",
  "definition": "1. The degree to which a material in environmental media can be assimilated by an organism.\n\n2. The degree to which a substance becomes available to the target tissue after administration or exposure.\n\n3. A measure of the physicochemical access that a toxicant has to the biological processes of an organism. The less the bioavailability of a toxicant, the less its toxic effect on an organism.\n\n4. Degree to which chemicals can be taken up by organisms.\n\n5. How easily a plant or animal can take up a particular contaminant from the environment.\n\n6. Degree of ability to be absorbed and ready to interact in organism metabolism.\n\n7. The ability of a substance to affect organisms.\n\n8. The rate and extent to which an agent can be absorbed by an organism and is available for metabolism or interaction with biologically significant receptors. Bioavailability involves both release from a medium (if present) and absorption by an organism.\n\n9. The ability to be absorbed and available to interact with the metabolic processes of an organism.\n\n10. A measure of the degree to which a dose of a substance becomes physiologically available to the body tissues depending upon adsorption, distribution, metabolism, and excretion rates.\n\n11. The availability of a compound for biodegradation, influenced by the compound's location relative to microorganisms and its ability to dissolve in water.\n\n12. The degree to which a substance becomes available to the target tissue after administration or exposure. [EPA 2003]\n\n13. The ability to be absorbed and available to interact with the metabolic processes of an organism. [EPA 2004]\n\n14. A measure of the degree to which a dose of a substance becomes physiologically available to the body tissues depending upon adsorption, distribution, metabolism, and excretion rates. [OAQPS 1989]\n\n15. The rate and extent to which an agent can be absorbed by an organism and is available for metabolism or interaction with biologically significant receptors. Bioavailability involves both release from a medium (if present) and absorption by an organism. [IPCS 2004]\n\n16. A measure of how much of a contaminant is absorbed when people are exposed to that contaminant through inhalation, skin contact or food intake.",
  "subject": "Science and research",
  "references": [
    "Waste and Cleanup Risk Assessment Glossary",
    "Integrated Risk Information System (IRIS) Glossary; EPA 2003",
    "Sediment Total Maximum Daily Loads (TMDLs) Glossary",
    "Aquatic Biodiversity Glossary; Biocriteria Glossary",
    "Ecological Risk Assessment Glossary of Terms",
    "Terms of Environment",
    "Contaminated Sediments Glossary & Acronyms",
    "Exposure Factors Handbook: Glossary",
    "EPA 2004",
    "OAQPS 1989",
    "Glossary of Technical Terms: Office of Underground Storage Tanks",
    "Thesaurus of Terms Used in Microbial Risk Assessment",
    "ExpoBox Terminology; EPA ExpoBox Terminology"
  ],
  "url": "https://mlchart.com/terminology/environment/bioavailability/"
}