Bioavailability

{
  "id": "MLC-T-CHM-001246",
  "term": "Bioavailability",
  "field": "Chemistry",
  "definition": "The fraction of an administered dose of a chemical substance that reaches the systemic circulation in an unchanged form and becomes available to exert its pharmacological or toxicological effects. It describes the rate and extent to which the active substance is absorbed from its site of administration. For orally administered drugs, bioavailability is often less than 100% due to incomplete absorption and first-pass metabolism.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "exposure"
  ],
  "references": [
    "PAC, 2004, 76, 1033. 'Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003)' on page 1041 (https://doi.org/10.1351/pac200476051033)",
    "PAC, 2004, 76, 1033. 'Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003)' on page 1040 (https://doi.org/10.1351/pac200476051033)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/bioavailability/"
}