MLchartDataset catalogue

Absolute bioavailability

Term · Chemistry · MLC-T-CHM-000048

The fraction of an administered dose of an unchanged drug that reaches the systemic circulation following administration by any route other than intravenous. It is determined by comparing the area under the plasma concentration-time curve (AUC) after extravascular administration to the AUC after intravenous administration. This value is expressed as a percentage or a fraction between 0 and 1.

Table 1. Record
IdentifierMLC-T-CHM-000048
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2009, 81, 971. 'Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009)' on page 973 (https://doi.org/10.1351/PAC-REC-04-10-14)
See alsoDosage form
Record as JSON
{
  "id": "MLC-T-CHM-000048",
  "term": "Absolute bioavailability",
  "field": "Chemistry",
  "definition": "The fraction of an administered dose of an unchanged drug that reaches the systemic circulation following administration by any route other than intravenous. It is determined by comparing the area under the plasma concentration-time curve (AUC) after extravascular administration to the AUC after intravenous administration. This value is expressed as a percentage or a fraction between 0 and 1.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "dosage form"
  ],
  "references": [
    "PAC, 2009, 81, 971. 'Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009)' on page 973 (https://doi.org/10.1351/PAC-REC-04-10-14)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/absolute-bioavailability/"
}

Record 50 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.