NY-ESO-1/LAGE-1 HLA class I/II peptide vaccine

{
  "id": "MLC-T-ONC-015571",
  "term": "NY-ESO-1/LAGE-1 HLA class I/II peptide vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cancer vaccine containing HLA class I- and II-binding peptides derived from the NY-ESO-1/LAGE-1 cancer/testis antigen with potential immunostimulatory and antineoplastic activities. Upon administration, NY-ESO-1/LAGE-1 HLA class I/II peptide vaccine may induce a cytotoxic immune response against tumor cells that over-express NY-ESO-1/LAGE-1. Rarely expressed by normal cells, the NY-ESO-1/LAGE-1 cancer/testis antigen has been shown to be preferentially expressed on the surface of some cancer cell types.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ny-eso-1-lage-1-hla-class-i-ii-peptide-vaccine/"
}