Active systemic anaphylaxis test

{
  "id": "MLC-T-CHM-000192",
  "term": "Active systemic anaphylaxis test",
  "field": "Chemistry",
  "definition": "A procedure for evaluating the potential of a substance to induce a severe, generalized allergic reaction in a sensitized animal. This test involves administering the test substance to an animal previously exposed to an allergen, then observing for signs of anaphylaxis such as respiratory distress, hypotension, or collapse. The severity of the reaction is often scored based on a standardized scale.",
  "synonyms": [
    "ASA test"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "anaphylactic shock"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1116 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/active-systemic-anaphylaxis-test/"
}