Anaphylaxis

{
  "id": "MLC-T-CHM-000568",
  "term": "Anaphylaxis",
  "field": "Chemistry",
  "definition": "A rapid, severe, and potentially fatal systemic hypersensitivity reaction mediated by immunoglobulin E (IgE) antibodies. It occurs upon re-exposure to an allergen, leading to widespread mast cell and basophil degranulation and the release of potent inflammatory mediators. Symptoms can include hives, angioedema, bronchospasm, and hypotension.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "allergy",
    "angioedema",
    "anaphylactic shock",
    "immediate-type hypersensitivity"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1122 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/anaphylaxis/"
}