Allergen

{
  "id": "MLC-T-CHM-000415",
  "term": "Allergen",
  "field": "Chemistry",
  "definition": "An antigenic substance, typically a protein or glycoprotein, that is capable of inducing a type I hypersensitivity (allergic) reaction in susceptible individuals upon re-exposure. The initial exposure sensitizes the immune system, leading to the production of immunoglobulin E (IgE) antibodies. Subsequent contact with the same allergen triggers the release of histamine and other inflammatory mediators from mast cells, causing the symptoms of an allergic response.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "immunostimulation",
    "antigenic",
    "contact allergen",
    "immediate-type hypersensitivity"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1120 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/allergen/"
}