Immunoglobulin E-binding Fc receptors

{
  "id": "MLC-T-CHM-005677",
  "term": "Immunoglobulin E-binding Fc receptors",
  "field": "Chemistry",
  "definition": "Cell surface proteins that specifically bind the Fc region of immunoglobulin E (IgE) antibodies. These receptors mediate allergic reactions by triggering the release of inflammatory mediators upon IgE binding and subsequent allergen cross-linking. High-affinity IgE receptors (FcεRI) are found on mast cells and basophils, while low-affinity receptors (FcεRII or CD23) are present on B lymphocytes and other immune cells.",
  "synonyms": [
    "IgE-binding FC receptors"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "CD23",
    "Fc receptor",
    "basophil",
    "mast cell"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1187 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/immunoglobulin-e-binding-fc-receptors/"
}