Fc receptor

{
  "id": "MLC-T-CHM-004361",
  "term": "Fc receptor",
  "field": "Chemistry",
  "definition": "A receptor protein on the surface of certain immune cells that binds the Fc tail region of an antibody. It couples antibodies to cellular effector functions: when pathogens coated with antibody (opsonized) bind Fc receptors on phagocytes, the cells engulf and destroy them, and on natural killer cells the binding triggers antibody-dependent cytotoxicity. Separate receptors exist for each antibody class, such as FcγR for IgG and FcεR for IgE.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "Fc fragment",
    "antibody-dependent cellular cytotoxicity",
    "isotype"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1164 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/fc-receptor/"
}