Fd fragment

{
  "id": "MLC-T-CHM-004362",
  "term": "Fd fragment",
  "field": "Chemistry",
  "definition": "A proteolytic fragment of an immunoglobulin heavy chain, consisting of the variable region and the first constant domain (VH and CH1). This fragment remains associated with the light chain to form the Fab fragment, which is responsible for antigen binding. The Fd fragment is distinct from the Fc fragment, which mediates effector functions.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Fab fragment",
    "heavy chain",
    "light chain"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1164 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/fd-fragment/"
}