Fab fragment

{
  "id": "MLC-T-CHM-004320",
  "term": "Fab fragment",
  "field": "Chemistry",
  "definition": "A monovalent antigen-binding fragment of an immunoglobulin molecule, produced by papain digestion. This fragment consists of one light chain and the N-terminal half of one heavy chain, connected by a disulfide bond. It retains the ability to bind a single antigen epitope and is approximately 50 kDa.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "heavy chain",
    "light chain"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1164 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/fab-fragment/"
}