scFv

{
  "id": "MLC-T-CHM-010570",
  "term": "scFv",
  "field": "Chemistry",
  "definition": "A single-chain variable fragment, which is an engineered antibody fragment consisting of the variable regions of the heavy and light chains of an immunoglobulin, joined by a short, flexible peptide linker. This compact structure retains the antigen-binding specificity of the parent antibody. ScFvs are widely used in research, diagnostics, and therapeutic applications due to their small size and ease of production.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "heavy chain",
    "light chain",
    "variable region"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1241 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/scfv/"
}